Scientific Publications for Wound Management

Wunde

Evaluation of Acellular Intact Fish Skin Grafts for Treating Acute and Chronic Wounds 

Böddeker C, Biermann S, Jansen TM, Homey B, and Hoff NP International Wound Journal, no. 5 (2026): e70931 Published April 27th...

April 27, 2026

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Intact Fish Skin Grafting in a Patient With Hidradenitis Suppurativa

Am Surg. 92(4):1340-1344 Published April 9th, 2026 doi:10.1177/00031348251388957

April 9, 2026

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Application of acellular fish skin grafts for complicated soft-tissue wound management in multiple exotic companion animal species: Three cases (2023–2024)

Seebart C, Kunzman H, Cole G, Chen S Journal of Exotic Pet Medicine (57): 42-48 Published April 1st, 2026 doi:10.1053/j.jepm...

April 1, 2026

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DiabeticWunde

Intent to Treat Analysis of the Primary and Secondary Outcomes for the ODINN Intact Fish Skin Graft for Deep Diabetic Foot Wounds Trial. 

Dardari D, Piaggesi A, Potier L, et al. Int Wound J. 23(3):e70847. Published 2026 March doi:10.1111/iwj.70847

März 23, 2026

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The use of intact fish skin grafts in the treatment of acute complicated bite wounds: a case report 

Adamovic I, Mäder HD, Golowan A, et al. J Surg Case Rep (3):rjag197 doi:10.1093/jscr/rjag197

März 6, 2026

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Successful treatment of a necrotizing fasciitis related skin defect using fish skin grafting in a patient with extensive psoriasis vulgaris 

Al-Naesan I, Frischhut N, Schlosser W, Pixner D. JAAD Case Rep. 70:29-31 Published January 31st, 2026 doi:10.1016/j.jdcr.202...

Januar 31, 2026

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ChirurgischWunde

Kerecis and Recell in Patients with Necrotizing Fasciitis: Report of Our First Experience in Three Patients

Pellegrin K Ortiz KJ Mil Med. Published online 2025 December 22. doi:10.1093/milmed/usaf599

Dezember 22, 2025

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Comparison of intact fish-skin graft to standard of care for treatment of venous leg ulcers using real-world data from the USWR with 1:1 matching on 14 wound/patient factors

Miao H, Pine M, Lantis JC II, Fife C Int J Tissue Repair. 2025;1(1):[pages unknown]. Published 2025 October 31. doi:10.63676/j0khv...

Oktober 31, 2025

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Evaluation of intact fish skin grafts plus standard care in the treatment of venous leg ulcers: an interim analysis of the THOR trial

Serena TE, Tramelli B, Booker B, King E, Shi D, Lantis JC. Int J Tissue Repair. 2025;1(1). Published 2025 October 31. doi:10.6367...

Oktober 31, 2025

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VerbrennungenWunde

Evaluation of the Efficacy of Fish Skin Grafts as Wound Dressings: A Systematic Review

Ivana J, Sanjaya IGPH. Eur Burn J. 2025;6(3):50. Published 2025 Sep 8. doi:10.3390/ebj6030050.

September 8, 2025

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ChirurgischWunde

Acellular Fish Skin for Deep Dermal Traumatic Wounds Management: A Case Report

Biazar E, Heidari-Keshel S, Rezaee MS, Parsi P, Moravvej H, Tavirani MR  Clin Case Rep. 13(12):e71629. Published 2025 August 25. d...

August 25, 2025

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Intact fish skin graft for deep diabetic foot ulcers: results from the KEREFISH randomized controlled trial

Dardari D, Potier L, Sultan A, et al.  Diabetes Metab. Published online July 23, 2025. doi:10.1016/j.diabet.2025.101691

Juli 23, 2025

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Explosion-Related Polytrauma from Illicit Pyrotechnics: Two Case Reports and a Public Health Perspective

Fueth M, Bausen S, Schmidt SV, et al. Eur Burn J. 2025;6(2):31. Published 2025 Jun 3. doi:10.3390/ebj6020031

Juni 3, 2025

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Real-world outcomes of acellular fish skin grafts for chronic wounds: A retrospective analysis of effectiveness and costs

Dinter P, Weiss L, Navarini AA, Mueller SM.  Wound Repair Regen. 2025;33(3):e70019. doi:10.1111/wrr.70019

Juni 1, 2025

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The Effect of Intraoperative Use of Intact Fish Skin Grafts for High-Risk Patients With Class 3 and Class 4 Wounds Who Undergo Urgent/Emergent Abdominal Surgery

Bagin SV, Ellis CN, Sorfazian A, et al. Am Surg. 2025;91(9):1548-1550. doi:10.1177/00031348251346535

Mai 31, 2025

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Treatment of soft tissue radionecrosis with intact fish skin graft

Zhivov EV, Vague M, Ortega-Loayza AG. JAAD Case Rep. 2025 May 28;62:46-49. doi: 10.1016/j.jdcr.2025.05.002. PMID: 40661110; PMCID:...

Mai 28, 2025

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Serial irrigation and debridement with the use of Kerecis in the treatment of necrotizing fasciitis

Erickson CT, Garner RD, Manseau KA, Frisbie JA, Orth C. Trauma Case Rep. 2025;58:101196. Published 2025 May 27. doi:10.1016/j.tcr....

Mai 27, 2025

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Eyelid reconstruction using intact fish skin xenograft following periorbital necrotizing fasciitis

Shott M, Wang D, Nguyen J.  Front Ophthalmol (Lausanne). 2025;5:1589771. Published 2025 May 22. doi:10.3389/fopht.2025.1589771

Mai 22, 2025

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Innovative Materials

Plock, J., Tafrishi, B., Senn, A.S. (2025). Tiplica, GS., Isoherranen, K. (eds) Wound Healing. Springer, Cham

Mai 17, 2025

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Omega-3 Acellular Fish Skin Grafts for Chronic and Complicated Wounds: A Systematic Review of Efficacy and Safety

Karhana S, Khan MA. Dermatol Pract Concept. 2025;15(2):4945. Published 2025 Apr 1. doi:10.5826/dpc.1502a4945.

April 1, 2025

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Fish Skin Acellular Dermal Matrix Combined With Negative Pressure Wound Therapy for Diabetic Foot Ulcers

Tan APP, Chng JK. Cureus. 2025;17(3):e80488. Published 2025 Mar 12. doi:10.7759/cureus.80488

März 12, 2025

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Post-Mohs Surgical Wounds Treated With Intact Fish Skin Graft: A Multicenter Analysis

O’Quinn R, Aldridge C, Sax DS. Wounds. 2025 March; 37(3):102-106. doi:10.25270/wnds/24117.

März 1, 2025

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Acellular fish skin grafts in diabetic foot ulcer care: Advances and clinical insights

Zhao Y, Shen QQ. World J Diabetes. 2025;16(1):100597. doi:10.4239/wjd.v16.i1.100597

Januar 15, 2025

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Intact fish skin graft a new hope for the treatment of diabetic foot ulcers: A case report

Jugnet AC, Benard T, Lequint C, et al. World J Diabetes. 2024;15(12):2353-2359. doi:10.4239/wjd.v15.i12.2353

Dezember 15, 2024

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Hooked on Healing – Fish Skin Grafts for Diabetic Foot Ulcers

Castellani L, Arruda S. NEJM Evid. 2024;3(12):EVIDe2400373. doi:10.1056/EVIDe2400373

November 26, 2024

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Rapid Healing of Necrotizing Fasciitis Using the Kerecis Fish Skin Xenograft: A Clinical Case Report

Posner KM, Bakus C, Sodha S. Cureus. 2024;16(11):e73060. Published 2024 Nov 5. doi:10.7759/cureus.73060

November 5, 2024

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Intact Fish Skin Graft to Treat Deep Diabetic Foot Ulcers

Dured Dardari, M.D, Ph.D., Alberto Piaggesi, M.D., Louis Potier, M.D., Ariane Sultan, M.D., Holger Diener, M.D., Maude Francois, M...

Oktober 4, 2024

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The use of acellular fish skin grafts in burns and complex trauma wounds: a systematic review of clinical data

Pignet AL, Hecker A, Kamolz LP. Plast Aesthet Res. 2024;11:40. Published 2024 August 23. doi:10.20517/2347-9264.2024.54.

August 23, 2024

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Osteogenic differentiation and reconstruction of mandible defects using a novel resorbable membrane: An in vitro and in vivo experimental study

Bergamo P, de Í, Marcel Rodrigues Ferreira, et al. Journal of Biomedical Materials Research Part B Applied Biomaterials. 2023;111(...

Juli 20, 2024

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Acellular Fish Skin Grafts for Treatment of Periocular Skin Defects

Wang D, Maliakkal J, Sadat O, Vlad Codrea, Nguyen J. Ophthalmic plastic and reconstructive surgery. Published online May 31, 2024.

Mai 31, 2024

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Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix

Lee YJ, Han HJ, Shim HS. J Wound Care. 2024 May 2;33(5):348-356. doi: 10.12968/jowc.2024.33.5.348. PMID: 38683780.

Mai 2, 2024

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Skin and Bone: Intact Fish Skin to Reconstruct Traumatic Orbital Floor and Wall Defects

Steinberger EE, Vogt AZ, Tan JF. Ophthalmic Plastic and Reconstructive Surgery. Published online January 17, 2024.

Mai 1, 2024

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Acellular fish skin grafts in the treatment of diabetic wounds: Advantages and clinical translation

Zhao C, Feng M, Gluchman M, Ma X, Li J, Wang H. Journal of diabetes. 2024;16(5).

April 25, 2024

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Fish skin grafts versus standard of care on wound healing of chronic diabetic foot ulcers: A systematic review and meta-analysis

Ruiz-Muñoz M, Francisco-Javier Martinez-Barrios, Cervera-Garvi P, Lopezosa-Reca E, Marchena-Rodriguez AJ. Primary care diabetes. P...

April 1, 2024

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The Role of Fish Skin Xenografts in Healing Complex Wounds: A Brief Case Report

Daidone C, Salim N, Smith L, Raza A. Cureus. 2024 Mar 14;16(3):e56156. doi: 10.7759/cureus.56156. PMID: 38618405; PMCID: PMC110158...

März 14, 2024

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Efficacy of acellular fish skin graft in the management of chronic ulcer: a systematic review and meta-analysis

Gao J, Ge L, Gao Q, Zhang A, Hu L. Langenbeck s Archives of Surgery. 2024;409(1). doi:https://doi.org/10.1007/s00423-024-03230-1

Februar 16, 2024

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The Role of Fish Skin Xenografts in Healing Complex Wounds: A Brief Case Report

Camryn Daidone , Naved Salim , Leslie Smith , Ahsan Raza. Cureus. 2024

Januar 1, 2024

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Resolution of a chronic occipital wound with exposed skull bone with a fish skin graft: a successful treatment approach

Veitinger AB, Lippert BM, Fiedler LS. BMJ Case Reports. 2024;17(8):e261172. doi:https://doi.org/10.1136/bcr-2024-261172

Januar 1, 2024

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A Multicenter Retrospective Study Comparing a Polylactic Acid CAMP With Intact Fish Skin Graft or a Collagen Dressing in the Management of Diabetic Foot Ulcers and Venous Leg Ulcers.

Liden BA, Liu T, Regulski M, et al. A Multicenter Retrospective Study Comparing a Polylactic Acid CAMP With Intact Fish Skin...

Januar 1, 2024

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Exploring the Place of Fish Skin Grafts with Omega-3 in Pediatric Wound Management

Cherry I, Tarhini L, Doan M, De Buys Roessingh A. Journal of Clinical Medicine. 2024;13(1):112. doi

Dezember 25, 2023

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Acellular Fish Skin for Deep Dermal Traumatic Wounds Management; Introducing a Novel Dressing

Biazar E, Zandi R, Haidari-Keshel S, et al. Archives of academic emergency medicine. 2023;12(1):e14. doi:

November 27, 2023

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Consensus Recommendations for Optimizing the Use of Intact Fish Skin Graft in the Management of Acute and Chronic Lower Extremity Wounds

Anthony Tickner, Frank Aviles PT, Robert Kirsner, MD, PhD, Eric Lullove DPM, Leah Main, Mark Suski, Naz Wahab, John C. Lantis II I...

November 1, 2023

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The Use of Intact Fish Skin Grafts in the Treatment of Necrotizing Fasciitis of the Leg: Early Clinical Experience and Literature Review on Indications for Intact Fish Skin Grafts

Dueppers P, Bozalka R, Kopp R, et al. Journal of Clinical Medicine. 2023;12(18):6001.

September 16, 2023

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Acellular Fish Skin Graft Use in Open Abdomen Management

Rifat Latifi, Abbas Smiley. Surgical Technology International. 2023 Sept; Vol 40. DOI:10.52198/23.sti.42.gs1705

September 1, 2023

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Acellular Fish Skin for Tissue Replacement

Callie Horn, Allegra Fierro, John C Lantis. Surgical Technology International. 2023 Sep 20:42:sti42/1710. doi: 10.52198/23.STI.42....

September 1, 2023

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Fish Skin Graft: Narrative Review and First Application for Abdominal Wall Dehiscence in Children

Marco Di Mitri, Annalisa Di Carmine, Thomas E, et al. PubMed. 2023;11(9):e5244-e5244. doi:https://doi.org/10.1097/gox.000000000000...

September 1, 2023

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Acellular fish skin for wound healing

Ali Esmaeili, Esmaeil Biazar, Maryam Ebrahimi, Saeed Heidari Keshel, Bahareh Kheilnezhad, Farzaneh Saeedi Landi Int Wound J. 2023 ...

September 1, 2023

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A Systematic Review of Fish Based Biomaterial on Wound Healing and Anti-inflammatory Processes

A. John Paul, M. Gomathy, V. Krishnakumar. Advanced Wound Care (New Rochelle). 2024 Feb;13(2):83-96. doi: 10.1089/wound.2022.0142....

Juni 30, 2023

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Fish Skin Grafts Versus Alternative Wound Dressings in Wound Care: A Systematic Review of the Literature

Mohamed Ibrahim, Haneen S Ayyoubi, Layth A Alkhairi, Hozaifa Tabbaa, Isaac Elkins, Ravish Narvel Cureus. 2023 Mar; 15(3): e36348. ...

März 19, 2023

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Acellular fish skin for wound healing

Ali Esmaeili, Esmaeil Biazar, Maryam Ebrahimi, Saeed Heidari Keshel, Bahareh Kheilnezhad, Farzaneh Saeedi Landi Int Wound J. 202...

März 16, 2023

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A Bullous Eruption Following Apixaban Administration in Patient with Porphyria Cutanea Tarda

Wenger D, Tolson HC, Cuevas C, Sprout G, Covey R and Foster K. Clinical Case Report Int. 2023;7(1):1522. DOI: 10.25107/2638-4558.1...

Januar 1, 2023

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Final efficacy and cost analysis of a fish skin graft vs standard of care in the management of chronic diabetic foot ulcers: a prospective, multicenter, randomized controlled clinical trial

Lantis Ii JC, Lullove EJ, Liden B, et al. Wounds. 2023;35(4):71-79.

Januar 1, 2023

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Intact Fish Skin Graft vs. Standard of Care in Patients with Neuroischaemic Diabetic Foot Ulcers (KereFish Study): An International, Multicentre, Double-Blind, Randomised, Controlled Trial Study Design and Rationale.

Dardari D, Potier L, Sultan A, Francois M, M'Bemba J, Bouillet B, Chaillous L, Kessler L, Carlier A, Jalek A, Sbaa A, Orlando L, B...

Dezember 1, 2022

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Use of acellular intact fish skin grafts in treating acute paediatric wounds during the COVID-19 pandemic: a case series.

J Wound Care. Ciprandi G, Kjartansson H, Grussu F, Baldursson BT, Frattaroli J, Urbani U, Zama M. 2022 Oct 2;31(10):824-831. doi: ...

Oktober 1, 2022

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Successful upper extremity limb salvage using cellular- and tissue-based products in a patient with uncontrolled diabetes

Shawhin Rk Shahriari, Amanda C Ederle, Cees Whisonant, Joshua Harrison, Gregory Borah, Anil Shetty Wounds. 2022 Oct;34(10):E104-E...

Oktober 1, 2022

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Traumatic amputation: Healing the acute lawn mower injury- a case report

Amar Chandra, DPM. Ian Barron, DPM, FACFAS Published:September 13, 2022DOI:https://doi.org/10.1016/j.fastrc.2022.100247

September 13, 2022

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Faster Than Projected Healing in Chronic Venous and Diabetic Foot Ulcers When Treated with Intact Fish Skin Grafts Compared to Expected Healing Times for Standard of Care: An Outcome-Based Model from a Swiss Hospital

Zehnder T, Blatti M. The International Journal of Lower Extremity Wounds, 2022 May, 1-9. doi: 10.1177/15347346221096205 

Mai 1, 2022

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Use of Fish Skin in the Treatment of Chronic Lower Extremity Wounds: A Case Series Report

Michail Outos, Peter Nussbaumer J Surg 7: 1468 DOI: 10.29011/2575-9760.001468

Februar 22, 2022

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Intact fish skin grafts result in faster time to healing and lower costs to patients with venous leg ulcers and diabetic foot ulcers compared to the standard of care: An outcome-based pricing model.

Zehnder T, Blatti M, Journal of Wound Management, 2022, 23(1): 23-33.

Januar 1, 2022

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Evaluating the effect of omega-3–rich fish skin in the treatment of chronic, nonresponsive diabetic foot ulcers: penultimate analysis of a multicenter, prospective, randomized controlled trial.

Lullove EJ, Liden B, McEneaney P, et al. Wounds. 2022;34(4):e34-e36. doi:10.25270/wnds/2022.e34e36

Januar 1, 2022

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Fish Skin Grafts with Omega-3 for Treatment of Chronic Wounds: Exploring the Role of Omega-3 Fatty Acids in Wound Healing and A Review of Clinical Healing Outcomes.

Seth N, Chopra D, Lev-Tov H. [published online ahead of print, 2022 Apr 28]. Surg Technol Int. 2022, 40:sti40/1494.

Januar 1, 2022

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Curing Necrotic Angiodermatitis with an Intact Fish Skin Graft in a Patient Living with Diabetes.

Dardari, Dured, Corinne Lequint, Anne C. Jugnet, Tatiana Bénard, Marie Bouly, and Alfred Penfornis. 2022. Medicina 58, no. 2: 292

Januar 1, 2022

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Skin substitutes for the treatment of chronic wounds in patients with cancer: A retrospective case series

Joseph R Stoll, Sarah J Noor, Stephen W Dusza, Alina Markova J Am Acad Dermatol. 2021 Nov;85(5):1331-1333. doi: 10.1016/j.jaad.20...

November 1, 2021

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A Multicenter, Blinded, Randomized Controlled Clinical Trial Evaluating the Effect of Omega-3-Rich Fish Skin in the Treatment of Chronic, Nonresponsive Diabetic Foot Ulcers

Lullove EJ, Liden B, Winters C, McEneaney P, Raphael A, Lantis II JC. Wounds. 2021 Apr 14:WNDS20210414-1. Epub ahead of print. PMI...

April 14, 2021

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The Evidence for Antimicrobial and Hard to Infect Regenerative Matrices.

Ray K, Khajoueinejad N, Park S, Chan M, Lee J, Lantis JC 2nd. Surg Technol Int. 2021 Dec 6;39:75-82.

Januar 1, 2021

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A rare case report of neonatal calcinosis cutis induced by distant and delayed extravasation of intravenous calcium gluconate.

Ahn KH, Park ES. Arch Plast Surg. 2021, 48(6):641-645.

Januar 1, 2021

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The Utility of Novel Fish-Skin Derived Acellular Dermal Matrix (Kerecis) as a Wound Dressing Material

Kim, Tae & Park, Jun & Jeong, Hyun & Wee, Syeo. Journal of Wound Management and Research. 2021; 17. 39-47. 10.22467/jwmr.2020.0122...

Januar 1, 2021

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Use of Direct Peritoneal Resuscitation for Intra-Abdominal Catastrophes: A Technical Note.

Matthew McGuirk 1, Agon Kajmolli 1, Mahir Gachabayov 1, Ansab Haider 1, Matthew Bronstein 1, Dawn Spatz 1, Carlo Gwardshaladse 1, ...

November 1, 2020

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Cost Effectiveness of Fish Skin Grafts Versus Standard of Care on Wound Healing of Chronic Diabetic Foot Ulcers: A Retrospective Comparative Cohort Study

Christopher Winters; Robert S. Kirsner, PhD; David J. Margolis, PhD; and John C. Lantis, II,Wounds 2020;32(10):283–293.

Januar 1, 2020

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Improved skin regeneration with acellular fish skin grafts

Gabriella Fiakos, Zeming Kuang, Evan Lo Engineered Regeneration 1(2020), 95-101

Januar 1, 2020

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Fish-Skin Grafts Compared to Human Amnion/Chorion Membrane Allografts: A Double-Blind, Prospective, Randomized, Clinical Trial of Acute Wound Healing

Robert S. Kirsner, MD PhD1; David J. Margolis, MD PhD2; Baldur T. Baldursson, MD PhD3; Kristin Petursdottir, MD3, Olafur B. Davids...

September 1, 2019

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Acellular fish skin matrix on thin-skin graft donor sites: a preliminary study

Nathalie Badois, MD; Pierre Bauër, PhD; Maxime Cheron, RN; Caroline Hoffmann, MD; Marguerite Nicodeme, RN; Olivier Choussy, MD PhD...

September 1, 2019

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Treatment of diabetic foot wounds with acellular fish skin graft rich in omega-3: a prospective evaluation

Tania Woodrow, DPodM MSc,Theresa Chant, BSc RGN, Harvey Chant, BSc MB BS FRCS MD. Journal of Wound Care Vol 28, no 2, February 201...

Februar 1, 2019

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Acellular Fish Skin Graft Use for Diabetic Lower Extremity Wound Healing: A Retrospective Study of 58 Ulcerations and a Literature Review

Shannon Michael, Christopher Winters, Maliha Khan. Wounds 2019;31(10):262–268.

Januar 1, 2019

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Fish skin acellular dermal matrix: potential in the treatment of chronic wounds

Munir Patel, John C Lantis. Chronic Wound Care Management and Research 2019:6 59–70.

Januar 1, 2019

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Fish Skin to Heal Wounds

Christopher L. Winters, DPM, CWS-P. November/December 2018 | Podiatry Management.

Dezember 1, 2018

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Wound dehiscence on a diabetic patient with haemophilia and high risk of furtheramputation successfully healed with omega-3 rich fish skin: a case report

Christopher Winters. The Diabetic Foot Journal Vol 21 No 3 2018

November 3, 2018

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Clinical innovation: fish-derived wound product for cutaneous wounds.

Tellef Simonstad Sitje, Eirik Cornelius Grøndahl, Jens Ahm Sørensen.Wounds International. 2018;9(4):44–50.

September 4, 2018

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Marine Omega-3 Wound for the Treatment of Complicated Wounds: A Multi-Center Report.

B. Dorweiler, T. T. Trinh, F. Dünschede, C. F. Vahl, E. S. Debus, M. Storck, H. Diener. Gefässchirurgie, 2017 Dec 1;22(8):558–67....

Dezember 1, 2017

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Local Wound Therapy of a Chronic Resistant Venous Ulcer with Omega3 Wound Matrix: An Unconventional Procedure for the Therapy of Chronic Wounds.

A. Cyrek, J. Bernheim, B. Juntermanns1, A. Paul. Phlebologie, 2017 Jul 46: 353–357.

Juli 1, 2017

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When the Fish Gives the Thrust – Granulation Tissue in Case of Poor Circulation.

T. J. Clasen, E. Libich, M. Feldman. Wund Management, 2017 Apr;11(4):183-186.

April 11, 2017

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A Prospective, Postmarket, Compassionate Clinical Evaluation of a Novel Acellular Fish-skin Graft Which Contains Omega-3 Fatty Acids for the Closure of Hard-to-heal Lower Extremity Chronic Ulcers.

Chun K. Yang MD; Thais O. Polanco MD; and John C. Lantis II MD FACS. WOUNDS: A Compendium of Clinical Research and Practice, 2016 ...

April 28, 2016

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Marine Omega3 Wound Matrix for the Treatment of Complicated Wounds.

T. T. Trinh; F. Dünschede; C.-F. Vahl; B. Dorweiler. Phlebologie. 2016 Apr;45(2):93-98.

April 1, 2016

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Healing Rate and Autoimmune Safety of Full-Thickness Wounds Treated With Fish Skin Acellular Dermal Matrix Versus Porcine Small-Intestine Submucosa: A Noninferiority Study.

Baldur T. Baldursson MD PhD, H. Kjartansson MD, Fifa Konradsdóttir MSc, Palmar Gudnason MSc, G. F. Sigurjonsson MSc Eng and Sigrun...

März 14, 2015

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