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Accelerate Burn Healing with Fish Skin

Optimize your patients’ burn care and recovery
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Severe burns are traumatic and physically debilitating for patients, who may experience slow healing rates, infection, pain, and hypertrophic scarring during their recovery.

Backed by industry-leading clinical data, Kerecis’ GraftGuide can optimize your patients’ burn care and recovery. Made of intact fish skin, GraftGuide is clinically proven to accelerate burn wound healing, while reducing complications, length of stay, and scarring.

Kerecis for Burn Management

Accelerate healing & reduce complications [1-3]

reduce patient length of stay [4,5]

Regenerate organized tissue & help minimize scarring [6-8]

Kerecis GraftGuide® Products

Kerecis GraftGuide is intact fish skin especially developed for the management of burn wounds and donor sites.

The Kerecis fish‑skin grafts contain natural components and are available in multiple shapes, variants, and sizes.

The product classifies as a medical device and consists of a full thickness fish-skin that has been processed using Kerecis’ proprietary EnviroIntact™ method.

GraftGuide® Mano

The intact fish-skin graft in the shape of the hand to easily allow application on its complex 3D structure. Available in two sizes, medium and large, and in either left or right versions, for use in palmar or dorsum applications. Designed to reduce operation time when managing hand burn injuries.

Mano
Mano
Mano

GraftGuide Meshed 2:1

2:1 pre-meshed intact fish-skin graft designed to expand and cover larger wounds. Provides a viable clinical and economic solution for large wounds.

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GraftGuide Meshed
Using Kerecis, we have closed everything from a one-year chronic wound… to diabetic foot ulcers, to venous stasis ulcers, to burn wounds.
Carrie McGroarty
, PA-C, Raleigh, NC
Carrie McGroarty is a paid consultant of Kerecis

See how Kerecis Helped Burn Survivor Pétur Oddsson

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Burn Case Brochure
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GraftGuide Brochure
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GraftGuide Size Chart
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From the town of Isafjordur in northwest Iceland, Kerecis develops, manufactures, and sells patented fish skin soft tissue regeneration products that have regulatory approval in the United States, Europe and several other jurisdictions.

Important Information

This website and its content is not intended to provide diagnosis, treatment, or medical advice. Products, services, information, and other content provided on this website, including information provided directly or through links to third-party websites, are for informational purposes only. Information on this website should not be considered a substitute for professional advice from a healthcare provider. Always consult with a physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options.

Products and their variations may not be available in all countries and could be known under different trade names. Products, product names, indications, and claims vary by jurisdiction. Always verify with your local healthcare professional and consult the printed package information before use. Information on this website may not be current and might not reflect the latest product labeling – please refer to latest IFU’s on the website. For questions about product availability, please contact your Kerecis representative or use the contact form on our website.

Products are derived from fish sources and should not be used in patients with a known allergy to fish or sensitivity to fish products. Note that fish allergy is distinct from shellfish allergy. Do not apply fish skin products over infected or deteriorating wounds until the underlying cause has been resolved.

SurgiClose Silicone and Shield products contain silicone and are not suitable for patients with silicone sensitivity.
SurgiBind is not indicated for procedures requiring load-bearing support, such as hernia repair, for intraperitoneal organ contact, or where a bridging effect is needed.
SurgiBind Tendon Protect is not indicated to replace or repair the damaged tendon or to reinforce the strength of any tendon repair.
Always follow the product’s labeling for indications and contraindications.

A surgeon must always rely on their professional clinical judgment when deciding whether to use a specific product for a patient. Kerecis does not dispense medical advice and strongly recommends that surgeons be adequately trained in the use of its products before employing them in surgical procedures. The information provided on this website is intended to demonstrate the product offerings and should not replace the package insert, product label, or instructions for use. For regulatory and medical practice reasons, product availability may vary by market. Contact your Kerecis representative for further clarification.

  • For single patient use only; do not reuse, reprocess, or re-sterilize.
  • Discard any unused portions of the product.
  • Sterile only if the package is unopened and undamaged.
  • Do not use the product if the package seal has been broken, unintentionally opened, or if handling has caused damage or contamination.
  • Do not use after the expiration date printed on the product label or packaging.
  • Remove all non-viable and necrotic tissue prior to application of the product.
  • Remove exudate and control bleeding prior to product application.
  • Do not use in patients with known fish allergies.
  • The product is not designed, sold, or intended for use except as indicated.
  • No clinical trials have been conducted in pediatric, pregnant, or breastfeeding populations.

1

Stone R, Saathoff EC, Larson DA, et al. Accelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft. Int J Mol Sci. 2021;22(4):1590. doi:10.3390/ijms22041590 

2

Fierro AL, Bridge M, Hijazi N, Youssef G, Lantis JC 2nd. Intact Fish Skin Graft for the Treatment of Burns: Deep Partial Thickness Burns and Beyond. Surg Technol Int. 2025 Jan 16;45:sti45/1836. doi: 10.52198/25.STI.45.WH1836. Epub ahead of print. PMID: 39821348.   

3

Wallner, C. et al. (2022). The use of intact fish skin as a novel treatment method for deep dermal burns following enzymatic debridement: A retrospective case-control study. European Burn Journal, 3(1), 43–55. 

4

Magnusson S, et al. Regenerative and Antibacterial Properties of Acellular Fish Skin Grafts and Human Amnion/Chorion Membrane: Implications for Tissue Preservation in Combat Casualty Care. Mil Med. 2017;182(S1):383-388. doi:10.7205/ MILMED-D-16-00142 

5

Stauback R et al. The Use of Fish Skin Grafts in Children as a New Treatment of Deep Dermal Burns—Case Series with Follow-Up after 2 Years and Measurement of Elasticity as an Objective Scar Evaluation,J Clin Med. 2024 Apr 19;13(8):2389. doi: 10.3390/jcm13082389 

6

Lantis II JC, et al. Final efficacy and cost analysis of a fish skin graft vs standard of care in the management of chronic diabetic foot ulcers: a prospective, multicenter, randomized controlled clinical trial. Wounds. 2023;35(4):71-79. doi:10.25270/wnds/22094 

7

Heitzmann et al. Accelerated wound healing of enzymatically debrided deep dermal burn wounds after the use of fish skin in comparison to Suprathel. Burns. 2025 June. doi: 10.1016/j.burns.2025.107471.

8

Yue B. Biology of the Extracellular Matrix: An Overview. J Glaucoma. 2014;23:S20-S23. doi:10.1097/IJG.0000000000000108.

9

Shupp J, McLawhorn M, Moffatt L. Fish Skin Compared to Cadaver Skin as a Temporary Coverage and Wound Bed Preparation for Full Thickness Burns: An Early Feasibility Trial. J Burn Care Res. 42:S124-S124. doi:doi:10.1093/jbcr/irab032.201