Final efficacy and cost analysis of a fish skin graft vs standard of care in the management of chronic diabetic foot ulcers: a prospective, multicenter, randomized controlled clinical trial
Lantis Ii JC, Lullove EJ, Liden B, et al. Wounds. 2023;35(4):71-79.
Use of Fish Skin Graft in Management of Combat Injuries Following Military Drone Assaults in Field-Like Hospital Conditions.
Reda F, Kjartansson H, Jeffery SLA. Mil Med. 2023 Feb 15:usad028. doi: 10.1093/milmed/usad028. Epub ahead of print. PMID: 36794813.
Intact Fish Skin Graft vs. Standard of Care in Patients with Neuroischaemic Diabetic Foot Ulcers (KereFish Study): An International, Multicentre, Double-Blind, Randomised, Controlled Trial Study Design and Rationale.
Dardari D, Potier L, Sultan A, Francois M, M’Bemba J, Bouillet B, Chaillous L, Kessler L, Carlier A, Jalek A, Sbaa A, Orlando L, Bobony E, Detournay B, Kjartansson H, Bjorg Arsaelsdottir R, Baldursson BT, Charpentier G. Medicina (Kaunas). 2022 Dec 1;58(12):1775. doi: 10.3390/medicina58121775. PMID: 36556977; PMCID: PMC9786154.
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Use of acellular intact fish skin grafts in treating acute paediatric wounds during the COVID-19 pandemic: a case series.
J Wound Care. Ciprandi G, Kjartansson H, Grussu F, Baldursson BT, Frattaroli J, Urbani U, Zama M. 2022 Oct 2;31(10):824-831. doi: 10.12968/jowc.2022.31.10.824. PMID: 36240798.
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The Use of Acellular Fish Skin Grafts in Burn Wound Management—A Systematic Review.
Luze H, Nischwitz, SP, Smolle C, Zrim R, Kamolz L-P. Medicina, 2022, 58, 912. https://doi.org/10.3390/medicina58070912
Faster Than Projected Healing in Chronic Venous and Diabetic Foot Ulcers When Treated with Intact Fish Skin Grafts Compared to Expected Healing Times for Standard of Care:
Zehnder T, Blatti M. The International Journal of Lower Extremity Wounds, 2022 May, 1-9. doi: 10.1177/15347346221096205
Intact fish skin grafts result in faster time to healing and lower costs to patients with venous leg ulcers and diabetic foot ulcers compared to the standard of care: An outcome-based pricing model.
Zehnder T, Blatti M, Journal of Wound Management, 2022, 23(1): 23-33.
Evaluating the effect of omega-3–rich fish skin in the treatment of chronic, nonresponsive diabetic foot ulcers: penultimate analysis of a multicenter, prospective, randomized controlled trial.
Lullove EJ, Liden B, McEneaney P, et al. Wounds. 2022;34(4):e34-e36. doi:10.25270/wnds/2022.e34e36
Fish Skin Grafts with Omega-3 for Treatment of Chronic Wounds: Exploring the Role of Omega-3 Fatty Acids in Wound Healing and A Review of Clinical Healing Outcomes.
Seth N, Chopra D, Lev-Tov H. [published online ahead of print, 2022 Apr 28]. Surg Technol Int. 2022, 40:sti40/1494.
Wound healing ability of acellular fish skin and bovine collagen grafts for split-thickness donor sites in burn patients: Characterization of acellular grafts and clinical application.
Yoon J, Yoon D, Lee H, Lee J, Jo S, Kym D, Yim H, Hur J, Chun W, Kim G, Cho YS. Int J Biol Macromol. 2022, 14:S0141-8130(22)00291-4.
Curing Necrotic Angiodermatitis with an Intact Fish Skin Graft in a Patient Living with Diabetes.
Dardari, Dured, Corinne Lequint, Anne C. Jugnet, Tatiana Bénard, Marie Bouly, and Alfred Penfornis. 2022. Medicina 58, no. 2: 292
The Use of Intact Fish Skin as a Novel Treatment Method for Deep Dermal Burns Following Enzymatic Debridement: A Retrospective Case-Control Study.
Wallner C, Holtermann J, Drysch M, Schmidt S, Reinkemeier F, Wagner JM, Dadras M, Sogorski A, Houschyar KS, Becerikli M, Lehnhardt M, Behr B.
European Burn Journal. 2022; 3(1):43-55. https://doi.org/10.3390/ebj3010006
The Evidence for Antimicrobial and Hard to Infect Regenerative Matrices.
Ray K, Khajoueinejad N, Park S, Chan M, Lee J, Lantis JC 2nd. Surg Technol Int. 2021 Dec 6;39:75-82.
A rare case report of neonatal calcinosis cutis induced by distant and delayed extravasation of intravenous calcium gluconate.
Ahn KH, Park ES. Arch Plast Surg. 2021, 48(6):641-645.
Lipid mediator profiles of burn wound healing: Acellular codfish skin grafts promote the formation of EPA and DHA derived lipid mediators following seven days of treatment.
Aristotelis Kotronoulas , Adrián López García de Lomana , Sigurður Trausti Karvelsson, Marieke Heijink, Randolph Stone II, Martin Giera, Ottar Rolfsson. Prostaglandins Leukot Essent Fatty Acids. 2021 Dec;175:102358.
A Multicenter, Blinded, Randomized Controlled Clinical Trial Evaluating the Effect of Omega-3-Rich Fish Skin in the Treatment of Chronic, Nonresponsive Diabetic Foot Ulcers
Lullove EJ, Liden B, Winters C, McEneaney P, Raphael A, Lantis II JC. Wounds. 2021 Apr 14:WNDS20210414-1. Epub ahead of print. PMID: 33872197.
The Utility of Novel Fish-Skin Derived Acellular Dermal Matrix (Kerecis) as a Wound Dressing Material
Kim, Tae & Park, Jun & Jeong, Hyun & Wee, Syeo. Journal of Wound Management and Research. 2021; 17. 39-47. 10.22467/jwmr.2020.01228.
Accelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft
Stone, Randolph, II; Saathoff, Emily C.; Larson, David A.; Wall, John T.; Wienandt, Nathan A.; Magnusson, Skuli; Kjartansson, Hilmar; Natesan, Shanmugasundaram; Christy, Robert J.Int. J. Mol. Sci. 2021; 22(4): 1590.
Use of Direct Peritoneal Resuscitation for Intra-Abdominal Catastrophes: A Technical Note.
Matthew McGuirk 1, Agon Kajmolli 1, Mahir Gachabayov 1, Ansab Haider 1, Matthew Bronstein 1, Dawn Spatz 1, Carlo Gwardshaladse 1, Rifat Latifi. SURGICAL TECHNOLOGY INTERNATIONAL Volume 37 – Nov, 2020 – PMID:33245138
Cost Effectiveness of Fish Skin Grafts Versus Standard of Care on Wound Healing of Chronic Diabetic Foot Ulcers: A Retrospective Comparative Cohort Study
Christopher Winters; Robert S. Kirsner, PhD; David J. Margolis, PhD; and John C. Lantis, II,Wounds 2020;32(10):283–293.
One-Year Outcome of a Piscine Soft Tissue Alternative Used in Mucogingival Procedures: A Clinical Case Series
Irina F. Dragan, A. Alejandro Garcia, Raabia Malik, Nadeem Y. Karimbux. The International Journal of Periodontics & Restorative Dentistry, 2020:40 4.
Wound healing grafts: Omega-3 fatty acid lipid content differentiates the lipid profiles of acellular Atlantic cod skin from traditional dermal substitutes
Aristotelis Kotronoulas, Hulda S. Jónasdóttir, Rósa S. Sigurðardóttir, Skarphéðinn Halldórsson, Guðmundur G. Haraldsson, Óttar Rolfsson
Journal of Tissue Engineering and Regenerative Medicine 2020 Mar;14(3):441-451.
Improved skin regeneration with acellular fish skin grafts
Gabriella Fiakos, Zeming Kuang, Evan Lo Engineered Regeneration 1(2020), 95-101
Fish-Skin Grafts Compared to Human Amnion/Chorion Membrane Allografts: A Double-Blind, Prospective, Randomized, Clinical Trial of Acute Wound Healing
Robert S. Kirsner, MD PhD1; David J. Margolis, MD PhD2; Baldur T. Baldursson, MD PhD3; Kristin Petursdottir, MD3, Olafur B. Davidsson MSc4; Dot Weir, RN, CWON, CWS5; John C. Lantis II MD FACS6. Wound Repair and Regeneration, published online ahead of print 11. September 2019.
Acellular fish skin matrix on thin-skin graft donor sites: a preliminary study
Nathalie Badois, MD; Pierre Bauër, PhD; Maxime Cheron, RN; Caroline Hoffmann, MD; Marguerite Nicodeme, RN; Olivier Choussy, MD PhD; Maria Lesnik MD; Florence Canoui Poitrine, MD PhD; Isabelle Fromantin, RN PhD. Journal Of Wound Care Vol 28, No 9, September 2019
Acellular Fish Skin Graft Use for Diabetic Lower Extremity Wound Healing: A Retrospective Study of 58 Ulcerations and a Literature Review
Shannon Michael, Christopher Winters, Maliha Khan. Wounds 2019;31(10):262–268.
Fish skin acellular dermal matrix: potential in the treatment of chronic wounds
Munir Patel, John C Lantis. Chronic Wound Care Management and Research 2019:6 59–70.
Acellular Fish Skin Grafts for Management of Split Thickness Donor Sites and Partial Thickness Burns: A Case Series.
Alam K, Jeffery SLA. Mil Med. 2019 Mar 1;184(Suppl 1):16-20. doi: 10.1093/milmed/usy280.
Treatment of diabetic foot wounds with acellular fish skin graft rich in omega-3: a prospective evaluation
Tania Woodrow, DPodM MSc,Theresa Chant, BSc RGN, Harvey Chant, BSc MB BS FRCS MD. Journal of Wound Care Vol 28, no 2, February 2019.
Fish Skin to Heal Wounds
Christopher L. Winters, DPM, CWS-P. November/December 2018 | Podiatry Management.
Acellular Fish Skin Grafts and Pig Urinary Bladder Matrix Assessed in the Collagen-Induced Arthritis Mouse Model
Skuli Magnusson, BSc, Hilmar Kjartansson, MD, Baldur Tumi Baldursson, MD, PhD, Katrin Astradsdottir, BSc, Magnus S. Ågren, DrMedSc, Hilmar Hilmarsson, PhD, Gudmundur Fertram Sigurjonsson, MEng. The International Journal of Lower Extremity Wounds, Article first published online: October 18, 2018.
Clinical innovation: fish-derived wound product for cutaneous wounds.
Tellef Simonstad Sitje, Eirik Cornelius Grøndahl, Jens Ahm Sørensen.Wounds International. 2018;9(4):44–50.
Wound dehiscence on a diabetic patient with haemophilia and high risk of further
amputation successfully healed with omega-3 rich fish skin: a case report
Christopher Winters. The Diabetic Foot Journal Vol 21 No 3 2018
Marine Omega-3 Wound for the Treatment of Complicated Wounds: A Multi-Center Report.
B. Dorweiler, T. T. Trinh, F. Dünschede, C. F. Vahl, E. S. Debus, M. Storck, H. Diener.
Gefässchirurgie, 2017 Dec 1;22(8):558–67.
Local Wound Therapy of a Chronic Resistant Venous Ulcer with Omega3 Wound Matrix: An Unconventional Procedure for the Therapy of Chronic Wounds.
A. Cyrek, J. Bernheim, B. Juntermanns1, A. Paul.
Phlebologie, 2017 Jul 46: 353–357.
When the Fish Gives the Thrust – Granulation Tissue in Case of Poor Circulation.
T. J. Clasen, E. Libich, M. Feldman.
Wund Management, 2017 Apr;11(4):183-186.
Regenerative and Antibacterial Properties of Acellular Fish Skin Grafts and Human Amnion/Chorion Membrane: Implications for Tissue Preservation in Combat Casualty Care.
Magnusson S, Baldursson BT, Kjartansson H, Rolfsson O, Sigurjonsson GF. Military Medicine, 2017 Mar;182(S1):383–8.
A Clinical Case Report to Evaluate a Piscine Xenograft in a Gingival Soft Tissue Augmentation Procedure.
Irina F. Dragan, DDS, MS, Mariana Caramida, DDS PhD student, Miha Pirc, DMD, Hilmar Kjartansson, MD, FACEM, Nadeem Karimbux, DMD, MMSc. Trends in Clinical Periodontology and Implant Dentistry, Elsevier, 2017.
Marine Omega3 Wound Matrix for the Treatment of Complicated Wounds.
T. T. Trinh; F. Dünschede; C.-F. Vahl; B. Dorweiler. Phlebologie. 2016 Apr;45(2):93-98.
A Prospective, Postmarket, Compassionate Clinical Evaluation of a Novel Acellular Fish-skin Graft Which Contains Omega-3 Fatty Acids for the Closure of Hard-to-heal Lower Extremity Chronic Ulcers.
Chun K. Yang MD; Thais O. Polanco MD; and John C. Lantis II MD FACS. WOUNDS: A Compendium of Clinical Research and Practice, 2016 Apr;28(4):112-8
Healing Rate and Autoimmune Safety of Full-Thickness Wounds Treated With Fish Skin Acellular Dermal Matrix Versus Porcine Small-Intestine Submucosa: A Noninferiority Study.
Baldur T. Baldursson MD PhD, H. Kjartansson MD, Fifa Konradsdóttir MSc, Palmar Gudnason MSc, G. F. Sigurjonsson MSc Eng and Sigrun H. Lund PhD. The International Journal of Lower Extremity Wounds. 2015 Mar;14(1):37-4.
Use of Acellular Fish Skin for Dura Repair in an Ovine Model: A Pilot Study.
Hilmar Kjartansson MD, Ingvar H. Olafsson MD, Sigurbergur Karason MD, Hjalti Thorisson MD, Baldur T. Baldursson MD PhD, Eggert Gunnarsson DVM, Einar Jorundsson DVM PhD, G. F. Sigurjonsson MEng. Open Journal of Modern Neurosurgery, 2015 Oct;5(4):124-136.
Decellularized Fish Skin: Characteristics that Support Tissue Repair.
Skuli Magnusson BSc, Baldur T. Baldursson MD PhD, Hilmar Kjartansson MD, Gudny E. Thorlacius MSc, Ivar Axelsson MSc, Ottar Rolfsson PhD, Petur H. Petersen PhD, G. Fertram Sigurjonsson MEng. The Icelandic Medical Journal, 2015 Dec;101(12):567-73.
Wound Treatment with Cod Skin – An Exciting Development for the Future.
Ann Marie Fagerdahl RN CNOR PhD. Sårmagasinet, 2017 Jun;(3):34-36.
Acceleration of Wound Healing Through Utilization of Fish Skin Containing Omega-3 Fatty Acids.
Skuli Magnusson BSc; Christopher L. Winters DPM, Baldur T. Baldursson MD PhD, Hilmar Kjartansson MD, Ottar Rolfsson PhD, G.F. Sigurjonsson MSc Eng. Today’s Wound Clinic. 2016 May; 10(5)
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The Symposium on Advanced Wound Care Spring. April 5-9, 2017. San Diego, California.
10th annual Translational to Clinical (T2C) Regenerative Medicine Wound Care Conference, March 9-11, 2017, The Ohio State University’s Ohio Union.
Wounds UK Annual Conference. 14-16 Nov 2016. Harrogate International Centre.
International State-of-the-Science Meeting on Minimizing the Impact of Wound Infections Following Blast-Related Injuries. 29 November – 1 December 2016. National Capital Region.
Asian Society for Vascular Surgery and the 11th Asian Venous Forum, October 20-23, 2016. Grand Hyatt Singapore, Singapore.
The Desert Foot, October 19-22, 2016. Sheraton Grand Phoenix, Phoenix, Arizona.
The Symposium on Advanced Wound Care Fall. October 7-9, 2016. Caesars Palace, Las Vegas.
Dreilandertagung. October 5-8, 2016. Bern, Switzerland.
Military Health System Research Symposium. August 15-18, 2016. Gaylord Palms Resort & Convention Center, Kissimmee, Florida,
The 12th International Symposium on Periodontics and Restoratvie Dentistry: Boston Marriott Copley Place, Boston, Massachusetts, June 16-19, 2016.
26th conference of European Wound Management Association, 10th Deutscher Wundkongress and the the 2nd WundD.A.C.H conference. May 11-13, 2016. Bremen, Germany.
Biologic Scaffolds for Regenerative Medicine, Ninth Symposium. April 28-30, 2016. Silverado Resort – Napa, California.
51st Annual Meeting of the Scandinavian Society for the Study of Diabetes April 21-22, 2016. Reykjavik, Iceland.
The 28th Annual Meeting of the Wound Healing Society, SAWC-Spring/WHS Joint Meeting: April 13–17, 2016, Georgia World Congress Center, Atlanta, Georgia, USA.
Kerecis is pioneering the use of fish skin and fatty acids in the globally expanding cellular therapy.
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