Hospital Outpatient Department
The application of Kerecis Marigen is reimbursed by Medicare in the HOPD setting using CPT codes 15271-15278. The Medicare National Payment Rate in 2026 is $755.08 for wound(s) less than 100 sq cm using CPT codes 15271 and 15275 (site of service 22).
Kerecis Marigen Expanse expands to wound(s) over 100 sq cm to economically treat large wounds in the HOPD setting. The Medicare National Payment rate in 2026 for CPT 15273 and 15277 is $2,107.97 (wounds greater than 100 sq cm).
The Kerecis Marigen products are billed using HCPCS code Q4158. The Medicare National Payment rate in 2026 is $127.14 per sq cm.
Q4158 Crosswalk
| HCPCS | CPT Code | Wound Size | Site of Service | 2026 Payment 15271-15278 | 2026 Payment Q4158 |
|---|---|---|---|---|---|
| Q4158 | 15271 | < 100 sq cm | HOPD (22) | $755.08 | $127.14 per sq cm |
| Q4158 | 15273 | > 100 sq cm | HOPD (22) | $2,107.97 | $127.14 per sq cm |
| Q4158 | 15275 | < 100 sq cm | HOPD (22) | $755.08 | $127.14 per sq cm |
| Q4158 | 15277 | > 100 sq cm | HOPD (22) | $2,107.97 | $127.14 per sq cm |
| Q4158 | 15271 | < 100 sq cm | ASC(24) | $404.93 | $127.14 per sq cm |
| Q4158 | 15273 | > 100 sq cm | ASC(24) | $1,128.57 | $127.14 per sq cm |
| Q4158 | 15275 | < 100 sq cm | ASC(24) | $94.66 | $127.14 per sq cm |
| Q4158 | 15277 | > 100 sq cm | ASC(24) | $1,128.57 | $127.14 per sq cm |
Ambulatory Surgical Center
The application of Kerecis Marigen is reimbursed by Medicare in the ASC setting using CPT codes 15271 – 15278. The Medicare National Payment rate in 2026 is $404.93 and $94.66 for CPT codes 15271 and 15275, respectively (wounds less than 100 sq cm). The Medicare payment rate in 2026 for wounds greater than 100 sq cm is $1,128.57 using CPT codes 15273 and 15277.
The Kerecis Marigen products using HCPCS code Q4158 is reimbursed by Medicare at $127.14 per sq cm in 2026.
Physician’s Office Setting
Kerecis has separate reimbursement for MariGen, Q4158, and Shield Adhesive, A2019, if applied in a physician’s office (site of service 11).
The Medicare physician fee schedule in 2026 for Q4158 and A2019 is $127.14 per sq cm.
Contact the Reimbursement Hotline at 844-KERECIS (844-537-3247) for Benefit Investigation and fee schedule information.
Email: reimbursement@kerecis.com
Reimbursement Hotline and Benefit Verification
Once you decide to use Kerecis® MariGen, our Reimbursement Hotline team will work closely with you throughout your benefit verification and prior authorization and update you on the policy status of Kerecis in your area.
If you have any questions about reimbursement for Kerecis® MariGen, contact us:
Email: reimbursement@kerecis.com
Reimbursement Hotline: 844-KERECIS (844-537-3247)
Fax: 844-529-3247