Hospital Outpatient Department
The application of Kerecis MariGen is reimbursed by Medicare in the HOPD setting using CPT codes 15271-15278. The Medicare National Payment Rate in 2026 is $755.08¹ for wound(s) less than 100 sq cm using CPT codes 15271 and 15275 (site of service 22).
Kerecis MariGen Expanse expands to wound(s) over 100 sq cm to economically treat large wounds in the HOPD setting. The Medicare National Payment rate in 2026 for CPT 15273 and 15277 is $2,107.97 (wounds greater than 100 sq cm).
The Kerecis MariGen products are billed using HCPCS code Q4158. The Medicare National Payment rate in 2026 is $127.14 per sq cm.
¹Medicare Reimbursement for CPT Application Code 15271, 15275, and 15273 is adjusted from the Medicare National Payment Rate based on the Facilities Wage Index.
Q4158 Crosswalk
| HCPCS | CPT Code | Wound Size | Site of Service | 2026 Payment 15271-15278 | 2026 Payment Q4158 |
|---|---|---|---|---|---|
| Q4158 | 15271 | < 100 sq cm | HOPD (22) | $755.08 | $127.14 per sq cm |
| Q4158 | 15273 | > 100 sq cm | HOPD (22) | $2,107.97 | $127.14 per sq cm |
| Q4158 | 15275 | < 100 sq cm | HOPD (22) | $755.08 | $127.14 per sq cm |
| Q4158 | 15277 | > 100 sq cm | HOPD (22) | $2,107.97 | $127.14 per sq cm |
| Q4158 | 15271 | < 100 sq cm | ASC(24) | $404.93 | $127.14 per sq cm |
| Q4158 | 15273 | > 100 sq cm | ASC(24) | $1,128.57 | $127.14 per sq cm |
| Q4158 | 15275 | < 100 sq cm | ASC(24) | $94.66 | $127.14 per sq cm |
| Q4158 | 15277 | > 100 sq cm | ASC(24) | $1,128.57 | $127.14 per sq cm |
Ambulatory Surgical Center
The application of Kerecis MariGen is reimbursed by Medicare in the ASC setting using CPT codes 15271 – 15278. The Medicare National Payment rate in 2026 is $404.93² and $94.66² for CPT codes 15271 and 15275, respectively (wounds less than 100 sq cm). The Medicare payment rate in 2026 for wounds greater than 100 sq cm is $1,128.57 using CPT codes 15273 and 15277.
The Kerecis MariGen products using HCPCS code Q4158 is reimbursed by Medicare at $127.14 per sq cm in 2026.
²Medicare Reimbursement for CPT Application Code 15271, 15275, and 15273 is adjusted from the Medicare National Payment Rate based on the Facilities Wage Index.
Physician’s Office Setting
Kerecis has separate reimbursement for MariGen, Q4158, and Shield Adhesive, A2019, if applied in a physician’s office (site of service 11).
The Medicare physician fee schedule in 2026 for Q4158 and A2019 is $127.14³ per sq cm.
Contact the Reimbursement Hotline at 844-KERECIS (844-537-3247) for Benefit Investigation and fee schedule information.
Email: reimbursement@kerecis.com
³Medicare Reimbursement on CPT Application Code 15271 – 15278 and Graft Product Q4158 and A2019 are subject to be adjusted according to the geographical location where services are provided
Reimbursement Hotline and Benefit Verification
Once you choose to use Kerecis® MariGen, our Reimbursement Hotline Team will work closely with your office throughout the benefit verification and prior authorization process. Customers will also be provided with ongoing updates regarding the reimbursement and policy status of Kerecis products in your area.
If you have any questions about reimbursement for Kerecis® MariGen, please contact us:
Email: reimbursement@kerecis.com
Reimbursement Hotline: 844-KERECIS (844-537-3247)
Fax: (844) 529-3247
Request a Virtual Meeting with one of our Field Reimbursement Team Members: Reimbursement Support
Book a Virtual Reimbursement Support Meeting: Reimbursement Support
Schedule a 30- or 60-minute virtual consultation with a Kerecis Field Reimbursement Team member. Available to both new and existing customers, these sessions provide personalized support for reimbursement-related questions and operational needs.
Topics include:
• Coverage & Benefits
• Billing & Coding
• Claims Submission
• Denials & Appeals
• Documentation Review
• Account Follow-Up
• New Customer Onboarding
• General Support
Appointments available Monday through Friday with flexible scheduling options.
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From the town of Ísafjörður in northwest Iceland, Kerecis develops, manufactures, and distributes patented fish-skin medical devices that support soft tissue regeneration in the body, with regulatory clearance in the United States, Europe, and beyond.