Kerecis GraftGuide™

Fish skin application for burns

GraftGuide is intact fish skin which is used to regenerate tissue on surgical, traumatic, and acute wounds (1). Because there is no risk of viral or prion disease transfer from North-Atlantic cod to humans, the fish skin only needs mild processing with our proprietary method (2). The GraftGuide products are regulated as medical devices and consist of a full thickness fish skin that has been processed using Kerecis’ proprietary EnviroIntact™ method.

GraftGuide is not available in all countries and may be known under different trade names. Products, product names, indications and claims vary between jurisdictions


Kerecis GraftGuide is indicated for the management of wounds including:

  • Partial and full thickness wounds
  • Trauma wounds
  • Surgical wounds (donor sites, post-Mohs surgery, post-laser surgery, podiatric, wound

Kerecis GraftGuide is produced from a fish source and should not be used in patients with a known allergy or other sensitivity to fish material.

Kerecis GraftGuide Instructions for Use (USA)


Not Healthcare Advice
This Site is not intended to provide diagnosis, treatment or medical advice. Products, services, information and other content provided on this Site, including information that may be provided on this Site directly or by linking to third-party websites, are provided for informational purposes only. Information on this Site should not be considered as a substitute for advice from a healthcare professional.  Please consult with a physician or other healthcare professional regarding any medical or health related diagnosis or treatment options.

Products are not available in all countries and may be known by different names than used on this web-page. Products, product names, indications and claims vary between countries. Always make sure to check with your local health care professional and read the actual printed package information prior to use. Information on this website might not be current and might not be an accurate reflection of current product labeling.

Surgeon Disclaimer
A surgeon must always rely on his or her own professional clinical judgment when deciding whether to use a particular product when treating a particular patient. Kerecis does not dispense medical advice and recommends that surgeons be trained in the use of any particular product before using it in surgery.

The information presented is intended to demonstrate the Kerecis product offerings. A surgeon must always refer to the package insert, product label and/or instructions for use before using any Kerecis product. Products may not be available in all markets because product availability is subject to the regulatory and/or medical practices in individual markets. Please contact your Kerecis representative if you have questions about the availability of Kerecis products in your area.

  1. Magnusson, S. et al. Decellularized fish skin: characteristics that support tissue repair. Laeknabladid 101, 567–573 (2015).
  2. Baldursson, B. T. et al. Healing rate and autoimmune safety of full-thickness wounds treated with fish skin acellular dermal matrix
    versus porcine small-intestine submucosa: a non-inferiority study. Int. J. Low. Extrem. Wounds 14, (2015).

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Kerecis vision is to extend human life by supporting the body’s own ability to regenerate